Both passive and active immunization approaches have demonstrated succes in animal models and human clinical trials.

The efficacy of active immunization with subunit vaccines from S.mutans has been proved to prevent dental caries in animal models.
However, there are few studies on efficacy in humans.

The primary target of such a vaccine would be young children, who are at high risk at this disease.

Risk-free and more effective approach to prevent human dental caries should be developed.

Recent advances in research on mucosal vaccines will lead to a safe and effective vaccine

Local passive immunization with monoclonal Ab specific for S.mutans antigens has received recently much attention.

These immunological approaches for preventing caries should be applicable to the control of various mucosal diseases.

i heard bout dat also few days bak

but it will do a loss to our operative deptt.

lol.............u bothered about ur operative dept or peoples health.......^^